과도한 폐 스트레칭 감지 바이오마커
문의하기
| 기술분야 | 보건/의료 |
|---|---|
| 개발상태 | Available for demonstration |
| 보유기관 | |
| 기술유형 | |
| 지식재산권 | IPR applied but not yet granted |
| 보유국가 | 스페인 |
- 제품소개
- Summary인공호흡기를 사용하는 환자의 폐의 과도한 스트레칭을 예측하는 바이오마커입니다. 폐 스트레칭의 양에 비례하는 점수로 표기하여 폐 스트레칭 진단 및 모니터링을 수행하며, 반복적인 측정을 통해 환자의 인공 호흡 설정을 최적화합니다.DescriptionLung damage associated with mechanical ventilation is caused by an increase in mechanical stress in the tissue, which triggers cell death and inflammation. This damage has been linked to a higher rate of death from disease in patients with lung damage. There are currently no specific biomarkers that specifically serve to monitor the level of mechanical stress that tissue is undergoing. The patent describes a new micro-RNA signature associated with mechanical stress in lung tissue and biological samples. After quantification, microRNAs are combined in a score proportional to the amount of lung stretch, allowing the diagnosis and monitoring of lung overstretching. Therefore, repeated measurements can help to optimize ventilatory setting in patients.Technology Keywords06001005 - Diagnostics, Diagnosis06002007 - In vitro Testing, Trials06001012 - Medical Research06002002 - Cellular and Molecular Biology06003002 - Gene Expression, Proteome ResearchMarket Application Keywords05001005 - Molecular diagnosis05001002 - In-vitro diagnosticsSector GroupHealthType and Role of Partner SoughtBiomedical/Biotechnological company interested in a license and/or a collaboration agreement to develop and exploit this asset.Type of Partnership ConsideredCommercial agreement with technical assistanceResearch and development cooperation agreement